TP Biosciences offers high-quality isotype control antibodies designed for flow cytometry (FCM), ELISA, immunohistochemistry (IHC), immunoprecipitation (IP), and Western blot (WB). These antibodies serve as critical negative controls to distinguish specific antibody binding from non-specific interactions, ensuring accurate and reliable experimental results.

Key Features of TP Biosciences Isotype Controls:

Matched to Experimental Antibodies – Same species, subclass, and conjugation format.
High Purity & Low Aggregation – Ensures minimal non-specific binding.
Validated for Multiple Applications – FCM, IHC, WB, ELISA, and IP.
Conjugated & Unconjugated Formats – Available with FITC, PE, APC, PerCP, Alexa Fluor, HRP, and biotin.
Low Endotoxin Levels (0.1-1 EU/µg) – Suitable for in vivo and in vitro studies.

Available Isotype Control Antibodies

1. Mouse Isotype Controls

IgG1, IgG2a, IgG2b, IgG3, IgA, IgM, IgE
Conjugated & Unconjugated Formats (e.g., FITC, PE, APC, PerCP)

2. Human Isotype Controls

Human IgG1, IgG2, IgG3, IgG4, IgA, IgM, IgE
Ideal for immunotherapy and checkpoint inhibitor research

3. Rabbit Isotype Controls

Rabbit IgG, IgA, IgM
For IHC, WB, and ELISA applications

4. Rat Isotype Controls

Rat IgG1, IgG2a, IgG2b, IgG2c, IgM
Commonly used in mouse model studies

5. Goat & Other Species

Goat IgG, Sheep IgG, Hamster IgG, Bovine IgG
For specific assay and model requirements

Applications of Isotype Controls:

 Flow Cytometry (FCM) – Controls for non-specific Fc receptor binding.
 Immunohistochemistry (IHC) – Negative controls for background staining.
 Western Blot (WB) & ELISA – Confirms specific antibody binding.
 Immunoprecipitation (IP) & Chromatin Immunoprecipitation (ChIP) – Ensures antibody specificity.
 In Vivo Studies – Serves as placebo or control antibodies.