Catalog #DRA220
| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| DRA220 | 50ug | $250.00 | ||
| DRA220 | 500ug | $1,800.00 | ||
| DRA220 | 1mg | $2,700.00 |
Recombinant SARS-CoV-2 S-trimer Protein is produced by our Mammalian expression system and the target gene encoding Cys15-Gln1208 is expressed with a 6His tag at the C-terminus. T19I, LPP24-26del, A27S, G142D, V213G, G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H and N969K mutations were identified in the SARS-CoV-2 variant (known as BA.2.12.1 lineage) which emerged in the US. Six proline substitutions and furin cleavage site substitutions are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
| Application fields | In Vitro Diagnostics |
|---|---|
| Protein Tag | C-6His |
| Species | SARS-CoV-2 |
| Alias | SARS-CoV-2 S protein; SARS-CoV-2 Spike glycoprotein; SARS-CoV-2 S glycoprotein; SARS-CoV-2 S-trimer Protein |
| Accession No | P0DTC2 |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 5% Trehalose, 10% Glycerol, pH 7.4. |
| Purity | > 95% by SDS-PAGE under reducing conditions |
| Expression System | Human Cells |