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Human GM2A Protein (C-His)

Catalog #P1020C1

Cat # Size Price Quantity
P1020C125µg$145.00
P1020C1100µg$295.00

Specifications

Expression SystemCHO
Protein TagC-His
Purity> 95% by SDS-PAGE under reducing conditions
Endotoxin< 1 EU per ug by the LAL method
ActivityPositive
ConjugateUnconjugated
SpeciesHuman
Accession NumberAAA35907.1
Protein SequenceSer32-Ile193
Molecular WeightThe recombinant human GM2A has the predicted molecular weight of 18.9 kD. The DTT-reduced protein migrates at approximately 20 kD on SDS-PAGE
FormulationPBS, pH 7.4 with 300mM NaCl (0.2 μm filtered)
Concentration25µg size is bottled at 0.2mg/mL concentration. 100 µg and 500 µg size is bottled at lot specific concentration.
PurificationAffinity Ni-NTA
ApplicationsELISA
FormatLiquid
ReconstitutionNA
Shipping ConditionCold Pack
Storage/Shelf LifeAn unopened vial can be stored at 4°C for 2 weeks or at -20°C and below for six months. This stock solution should be aliquoted and stored at -70°C to minimize the freeze/thaw cycles.
Background InformationThe human GM2A protein, also known as the ganglioside GM2 activator, is a small lipid transfer protein that acts as a cofactor for the lysosomal enzyme beta-hexosaminidase A. It plays a crucial role in the degradation of GM2 gangliosides and other molecules with terminal N-acetyl hexosamines. 
figure legend1Purified GM2A-FLAG on SDS-PAGE under non-reducing (P-) and reducing (P+) conditions. The purity of GM2A-FLAG is greater than 95%.
country of manufactureUSA
HazMat y/nN