| Expression System | HEK293 |
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| Protein Tag | C-His |
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| Purity | > 95% by SDS-PAGE under reducing conditions |
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| Endotoxin | < 1 EU per ug by the LAL method |
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| Activity | Positive |
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| Conjugate | Unconjugated |
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| Species | Human |
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| Accession Number | Q9H293-1 |
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| Protein Sequence | Tyr33-Gly177 |
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| Molecular Weight | The protein has a predicted MW of 17.6 kDa and migrates at approximately 25-30 kDa on SDS-PAGE with DTT-reduced condition. |
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| Formulation | Lyophilized powder from 0.22um filtered solution in PBS, pH 7.4, 8% trehalose |
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| Purification | Affinity Ni-NTA |
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| Applications | ELISA |
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| Format | Lyophilized |
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| Reconstitution | Centrifuge the tube before opening. Recommend reconstitute to a concentration > 100 ug/ml |
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| Shipping Condition | Ambient |
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| Storage/Shelf Life | <-20 °C for 12 months from the date of receipt; -80°C for 3 months after reconstitution. |
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| Background Information | Human Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17 family. It plays a key role in promoting Type 2 (Th2) immune responses, which are involved in allergic inflammation, helminth infections, and tissue repair. IL-25 signals through the IL-17RB receptor, leading to the activation of downstream pathways that induce cytokine production. |
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