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Human CD4 (C-Fc)

Catalog #P1085H2

Cat # Size Price Quantity
P1085H2100µg$295.00
P1085H21 mg$1,800.00

Specifications

Expression SystemHEK293
Protein TagC-Fc
Purity> 95% by SDS-PAGE under reducing conditions
Endotoxin< 1 EU per ug by the LAL method
ActivityPositive
ConjugateUnconjugated
SpeciesHuman
Accession NumberP01730
Protein SequenceLys26-Trp390
Molecular WeightThe protein has a predicted MW of 67.5 kDa. The protein migrates to 70-80 kDa on SDS-PAGE due to glycosylation.
FormulationLyophilized powder from 0.22um filtered solution in PBS, pH 7.4, 8% trehalose
PurificationProtein A
ApplicationsELISA
FormatLyophilized
ReconstitutionCentrifuge the tube before opening. Recommend reconstitute to a concentration > 100 ug/ml
Shipping ConditionAmbient
Storage/Shelf Life<-20 °C for 12 months from the date of receipt; -80°C for 3 months after reconstitution.
Background InformationHuman CD4 protein with a C-terminal Fc tag (C-hFc) is a recombinant protein produced in human cells, and is often used in research and development. This protein acts as a coreceptor for T cell receptors, interacting with MHC class II molecules and initiating intracellular signaling pathways. It's also a key component in the entry of HIV into target cells.