Product Details

Affinity resin is developed and established based on the principle of specific adsorption between biomolecules and other ligand molecules, aiming to purify target molecules through the specific adsorption between ligands on the resins and the target molecules. Protein A is a golden staphylococcal cell wall protein with a molecular weight of 42 kDa. It contains five structural domains that specifically bind to the Fc region of antibody IgG molecules.

By coupling modified Protein A ligands onto cross-linked agarose, arProtein A Focurose HR resin has been successfully developed. It is primarily used for the separation and purification of ascites fluid, cell culture supernatant, monoclonal antibodies, polyclonal antibodies, and Fc-tagged proteins derived from serum. With advantages such as high loading capacity, stable alkali resistance, excellent purification effect, and good reproducibility, arProtein A Focurose HR resin can significantly reduce the costs of customer affinity research and production by directly replacing other resins.

Features
Fast and simple (typically achieves purity of 95% or higher with a single purification step).
High loading capacity, fast flow rate, good alkali resistance, and easy to scale up.
Low ligand leaching rate and good reproducibility.