| Expression System | E.coli |
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| Protein Tag | No tag |
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| Purity | > 95% by SDS-PAGE under reducing conditions |
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| Endotoxin | < 0.05 EU per ug by the LAL method |
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| Activity | Positive |
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| Conjugate | Unconjugated |
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| Species | Human |
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| Accession Number | NP_061986.1 |
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| Protein Sequence | His29-Ser209 |
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| Molecular Weight | The protein has a predicted molecular weight of 20 kDa. The protein migrates at approximately 20-23 kDa on SDS-PAGE under reduced condition. |
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| Formulation | Lyophilized powder from 0.22um filtered solution in PBS, pH 7.4, 8% trehalose |
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| Purification | SEC |
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| Applications | ELISA |
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| Format | Lyophilized |
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| Reconstitution | Centrifuge the tube before opening. Recommend reconstitute to a concentration > 100 ug/ml |
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| Shipping Condition | Ambient |
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| Storage/Shelf Life | <-20 °C for 12 months from the date of receipt; -80°C for 3 months after reconstitution. |
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| Background Information | Fibroblast Growth Factor 21 (FGF-21) is a member of the fibroblast growth factor (FGF) family and functions as an endocrine metabolic regulator involved in glucose and lipid homeostasis. It is primarily secreted by the liver and acts as a hormone (hepatokine) to coordinate systemic energy balance under various metabolic conditions. FGF-21 exerts its biological activity through binding to fibroblast growth factor receptors (FGFRs)—particularly FGFR1c—in the presence of the co-receptor β-Klotho (KLB), forming an active signaling complex at the cell surface. |
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