8
Catalog #500058
| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 500058 | 1 mg | $250.00 | ||
| 500058 | 5 mg | $750.00 | ||
| 500058 | 20 mg | $2,000.00 |
Spartalizumab biosimilar is a humanized IgG4 monoclonal antibody targeting PD-1, a protein on T cells involved in immune regulation. It works by blocking the interaction between PD-1 and its ligands, PD-L1 and PD-L2, thereby preventing the inhibitory signals that usually suppress T-cell activation. This action leads to the activation of T cells and the stimulation of immune responses, making it useful for cancer immunotherapy. As a research-grade biosimilar, Spartalizumab is not intended for therapeutic use but is available for applications such as ELISA, neutralization assays, and bioanalytical assays.
| Clone | Spartalizumab |
|---|---|
| Reactivities | Human |
| Isotype | Human IgG4 |
| Recommended Isotype Control | Human IgG4 isotype control |
| Format | Liquid |
| Formluation | PBS, pH 7.4 |
| Sterility | 0.2 µm filtered |
| Clonality | Recombinant |
| Conjugation | Unconjugated |
| Immunogen | Human PD1 |
| Host | CHO cells |
| Purity | >95% (HPLC, SDS-PAGE) |
| Endotoxin | < 1.0 EU/mg (LAL assay) |
| Grade | In vivo ready (RUO) |
| Application | Neutralization; Flow Cytometry; ELISA; WB |
| Purification | Protein A |
| Storage Conditions | 2-8 °C, Avoid freeze / thaw cycle |
| Shelf Life | 6 months |
| Regulatory Status | RUO |