8

Anti-Human PD-1 (Spartalizumab Biosimilar)

Catalog #500058

Cat # Size Price Quantity
5000581 mg$250.00
5000585 mg$750.00
50005820 mg$2,000.00

Product Details

Spartalizumab biosimilar is a humanized IgG4 monoclonal antibody targeting PD-1, a protein on T cells involved in immune regulation. It works by blocking the interaction between PD-1 and its ligands, PD-L1 and PD-L2, thereby preventing the inhibitory signals that usually suppress T-cell activation. This action leads to the activation of T cells and the stimulation of immune responses, making it useful for cancer immunotherapy. As a research-grade biosimilar, Spartalizumab is not intended for therapeutic use but is available for applications such as ELISA, neutralization assays, and bioanalytical assays.

Specifications

CloneSpartalizumab
ReactivitiesHuman
IsotypeHuman IgG4
Recommended Isotype ControlHuman IgG4 isotype control
FormatLiquid
FormluationPBS, pH 7.4
Sterility0.2 µm filtered
ClonalityRecombinant
ConjugationUnconjugated
ImmunogenHuman PD1
HostCHO cells
Purity>95% (HPLC, SDS-PAGE)
Endotoxin< 1.0 EU/mg (LAL assay)
GradeIn vivo ready (RUO)
ApplicationNeutralization; Flow Cytometry; ELISA; WB
PurificationProtein A
Storage Conditions2-8 °C, Avoid freeze / thaw cycle
Shelf Life6 months
Regulatory StatusRUO