| Expression System | CHO Cells |
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| Protein Tag | C-His tag |
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| Purity | > 95% by SDS-PAGE under reducing conditions |
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| Endotoxin | < 1 EU per ug by the LAL method |
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| Activity | Positive |
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| Conjugate | Unconjugated |
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| Species | Human |
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| Accession Number | AAH29804.1 |
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| Protein Sequence | Met1-Pro242 |
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| Molecular Weight | The protein has a predicted MW of 27 kDa and migrates at approximately 35-40 kDa on SDS-PAGE with DTT-reduced condition. |
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| Formulation | Lyophilized powder from 0.22um filtered solution in PBS, pH 7.4, 8% trehalose |
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| Purification | Affinity Ni-NTA |
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| Applications | ELISA |
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| Format | Lyophilized |
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| Reconstitution | Centrifuge the tube before opening. Recommend reconstitute to a concentration > 100 ug/ml |
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| Shipping Condition | Ambient |
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| Storage/Shelf Life | <-20 °C for 12 months from the date of receipt; -80°C for 3 months after reconstitution. |
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| Background Information | Recombinant Human Interleukin-34 (IL-34) is a bioactive cytokine belonging to the interleukin-1 (IL-1) superfamily. IL-34 is a homodimeric glycoprotein that functions primarily as a ligand for the Colony Stimulating Factor-1 Receptor (CSF-1R), sharing this receptor with Macrophage Colony-Stimulating Factor (M-CSF). It plays a critical role in the differentiation, survival, and function of monocytes, macrophages, and microglia, and has been implicated in immune response regulation, neuroinflammation, and autoimmune diseases. |
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